How much know the toxic medicine of ear

How much know the toxic medicine of ear
The so far known toxic medicine of ear has nearly one hundred kinds, are mainly divided into 6 big classes. Antibiotic: Verify that toxic medicine of ear is mainly amino sugar glucoside antibiotic at present, they Streptomycin, pairs of the intersection of hydrogen and Streptomycin, neomycin, gentamicin, the intersection of purple perilla and mould plain, the intersection of Buddhist nun and the intersection of base of a fruit and mould plain, kanamycin, the intersection of man and the intersection of amine and the intersection of Carlos and those, in addition there is mould and plain through the ages, purple and mould and plain and chloromycetin,etc.. The one that relevant materials statistics show, amino sugar glucoside antibiotic caused accounts for about 1/3 of the deaf patient who happens deafly in recent years. Someone has counted more than 10,000 people, toxic incidence of ear of amino sugar glucoside antibiotic is: Gentamicin 8.6%, hold the cloth mouldly and plainly 6.1%, man amine kanamycin 13.9%, second base purple perilla is mould and plain (endure, take the place of the rice star) 2.4%. The toxicity to sense of hearing and vestibule system of these medicines can coincide, cause the deaf intensity to have individual differences. Discover, the mature baby is excessively sensitive to amino sugar glucoside toxicity at time when dissection and function of the inner ear are ripe. These medicines not only employ ear toxicity all over, the part of auris media is used to the inner ear also toxicant. Antineoplastic: There is toxic antineoplastic of ear that mainly has platinum types compounds, such as obey platinum, card platinum,etc., have the intersection of nitrogen and mustard, 6 - amino niacinamide, the intersection of Changchun and new alkali, the intersection of ether and the intersection of alcohol and the intersection of nitre and thiazole, two the intersection of chlorine and first the intersection of amine and purine, benzyl Yin thiazole sour, etc chlorine. Damage outside maos of cell at first along platinum, cause pairs of the intersection of side and deaf nerve nature of going on etc.. Card platinum damages the cochlear and vestibule. It is irreversible that what these medicines cause is deaf. Pan's diuresis medicine: Its hearing loss caused is mostly dual side symmetry, often with the tinnitus. If can park medicines give medicine, it is reversible to be deaf. If patients do not have good renal function, use medicine time passes the combination of toxic medicine of long and/or other ears, can cause permanent hearing losses. Have already found, Pan's diuresis medicine and amino sugar glucoside antibiotic have cooperative effect. This is because amino sugar glucoside antibiotic keep in touch with the intersection of inner ear and maos of cell membrane, it is penetrating to increase, Pan's diuresis medicine is entered in cells for higher density, causes and damages seriously. Resist malaria medicine: Quinine be employed extensively resist the intersection of malaria and medicine, can cause deafness and tinnitus, pass, if medicines stop in time, can return to normal, if does not stop medicines or is used in more easily infected group in time, can cause permanent hearing losses. Chloroquine can be caused deafly too. Medicine of all kinds of acid of bigcatkin willow: The most frequently used one is aspirin, namely acetyl salicylic acid. Medicine of all kinds of acid of bigcatkin willow is the most common medicines to cause the tinnitus, can cause symmetrical hearing loss of dual sides of 40 decibels at the same time, mostly reversible, but can also leave over serious tinnitus and permanent hearing loss. The medicine that the part uses: Dissolve in matchmaker types third two alcohol has ear toxicity, can make hair cells damage, can cause inflammation of auris media. Have ear toxic preservative have alcohol and the intersection of cresol and salt, getting clean to kill, forest, acetic acid Kui, iodine of chlorine, it washes to be must Thai, etc. In addition, medicine such as griseofulvin against mould can cause serious cochlear hair cells to lose; The perforation of the tympanic membrane person is some can't use sulphur willow mercury; Gathering the pyrrole ketone iodine of alkene has some cochlear toxicity, Herba Schizonepetae oil, tobacco and some heavy metal salt such as lead, mercury, arsenic, thallium, cadmium,etc. have ear toxicity.

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