What is the formation mechanism of the liver cirrhosis ascites? 's general knowledge

What is the formation mechanism of the liver cirrhosis ascites? 's general knowledge
(1)The plasma albumin is reduced: The plasma albumin is formated by the hepatocyte, the hepatocyte function obstacle at the time of liver cirrhosis, make the albuminous one reduce synthetically notably, thus make the colloid of blood plasma permeate, press, reduce. Under the participation of the high-pressure factor of pulse of door, some blood plasma is oozed, formed the ascites in the abdominal cavity from the door pulse blood vessel. It is generally acknowledged plasma albumin (2)Pulse pressure increases on the door: Now is already clear, the intersection of liver and inner fiber organize hyperplasia, cause blood vessel block in the liver when the liver cirrhosis, lead to the fact pulse pressure increases on the door, in addition, the blood plasma colloid permeates, presses, reduces this factor, make the fluid in the pulse system of the door apter to permeate through the abdominal cavity. (3)Lymphocytic to leak and increase: The intersection of regeneration and tubercle when the liver cirrhosis can cause the intersection of sex and the intersection of liver and vein block, lead to the fact lymphocytic to excrete the obstacle liver and the pressure increases behind the sinus, cause lymphocytically to leak to increase, some lymphocytic liquid will undoubtedly enter the abdominal cavity and cause the ascites. Can see lymphocytic liquid, make from the intersection of liver and the intersection of door and lymphocytic clump and liver lymphatic vessel leak under the membrane in operation, and find the chest conduit obviously increases thickly, it is equivalent to the intravenous requirements under the collar-bone sometimes. In addition, someone finds the guiding outside of lymphatic vessel can make the liver narrow, the ascites is reduced, pressure reducing and a vein of song bleed and stop in the spleen. So, someone points out the forming of the ascites relates to the fact that the lymphocytic liquid emerges excessively with guiding insufficiently. (4)Aldosterone,etc. increases: Aldosterone (there may be vasopressin) Tie and deactivate in the liver in normal cases, it is insufficient to the aldosterone and deactivation against hormone of diuresis that it can be caused that liver function is not complete, cause then sending aldosterone and vasopressin increase. These two kinds of hormone can be caused and carried the renal tubule and reabsorpted water, sodium to increase far, thus cause water, sodium further retention and form the ascites. (5)Renal function: Once ascites takes shape, because of the reduction of the blood capacity of effective circulation, make the pouring into amount of kidney reduce, thus make renal blood flow reduce, glomerular filtration rate is reduced. The latter can cause vasopressin to increase, these factors can be increasing water, sodium and carrying the tubular reabsorption of kidney and aggravating the intensity of the ascites far. (6)The third factor vigor is reduced: Find another function that the blood capacity of effective circulation reduces is to cause the vigor of the third factor to reduce in recent years. The third factor is arranging the sodium humoral factor of a kind of assumption, this factor can follow the change of the blood capacity, control the reabsorption to sodium of proximal renal tubule. Not complete in liver function and has ascites to form when the valid blood capacity is reduced, the vigor of this factor is lowered promptly, thus make the reabsorption of sodium increase. What took shape in the ascites in 3 kinds of factors played a leading role in early days ago the above-mentioned 6 kinds of factors, so the one that can be called the ascites and formed inspires the factor; And then 3 kinds of factors generate an important impact on the existing continuously of ascites after the ascites take shape, so can be called and maintained the factor. The ones that maintained the factor acted on retention that mechanisms are all water sodium commonly, the position that just acts on is different to some extent. Because these two major kinds of factors act on commonly, cause the ascites to take shape and exist continuously.
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