Liver transplantation can accept interferon jointly treats _'s treatment with virus thiazole while recuring by third liver person

Liver transplantation can accept interferon jointly treats _'s treatment with virus thiazole while recuring by third liver person
According to American scholar, recur third person who receives liver transplantation of liver as to minority, interferon (IFN - ) Jointly treat with virus thiazole safe and effectively.

A of Pittsburgh UPMC hepatopathy research center. Dr. Obaid Shakil points out, though IFN - and virus thiazole have already been applied to treating third liver extensively, but its function on the person who receives liver transplantation is not still clear. For this reason, researchers have carried on a preliminary test, in order to canvass its curative effect and security of the person who receives liver transplantation of recuring to third liver.

Researchers choose 38 to transplant more than patients (mean age is 50 years old for 6 months, 74% man, 91% 1 genotype virus infect) Carry on research, offer 3 million units of hypodermic injection IFN - , 3 times every week, oral virus thiazole 800 mg at the same time, it lasts 48 weeks once a day; Adopt the single treatment of virus thiazole for 24 weeks subsequently. The main terminal incident is replied for lasting virology, the secondary terminal incident includes jointly treating biochemistry, virology and histology when finishing to reply.

Researchers point out, 16 patients stop medicines, including 2 cases of myocardial infarction because of the bad reaction. Found finally, 7 (18%) It is having biochemistry to reply when finishing that jointly treating, 5 (13%) Virology is replied. Inflammatory activity to have person who replies virology have, change, but fiber take, aggravate.

In addition, virus thiazole can further reduce the serum transaminase level to treat to keep, but third liver virus (HCV) RNA level rises. In 38 patients, only have 2 examples (5%) It is replied that lasting virology happens. A lot of patients need to urge to usually treat red because of anaemia.

Dr., nbspShakil of , think IFN - and the intersection of virus and thiazole can treat minority, recur third person who receives liver transplantation of liver effectively, this treatment is apt to present the bad reaction, thus cause medicine decrement or stop medicines.
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