Intestines apt to defy syndrome and resist depressed to treat _'s treatment

Intestines apt to defy syndrome and resist depressed to treat _'s treatment
The intestines are apt to surge syndrome (IBS) ,Once called it in the past " Anaphylactic colon " , it is " apt to surge colon " Or " colitis of mucus " Wait,now it is referred to as in norm call by " intestines are apt to last syndrome " .
The intestines are apt to defy syndrome to be very common on clinic, it is one of the diseases of the enteric function disorder, account for 1% of the crowd, the morbidity is like showing a tendency to raise year by year, the therapeutic effect is not good enough. Often misdiagnosed on clinic as chronic colitis, indigestion and other diseases.
The intestines are apt to surge the clinical manifestation of syndrome for abdominal pain, abdominal distension, diarrhoea, belly discomfort, defecate and are used to changing and stool properties are unusual, the sustainability existence of symptom or intermittence breaks out. Its cause of disease is not so obvious, can't be explained through the way that any internal organs unusually dissect unusual or physiological biochemistry of the structure. IBS must get rid of the above-mentioned symptom that intestines and stomach disease cause, and the above-mentioned symptom that diseases such as chronic colitis, colon polyp, digestive tract tumour,etc. cause, the large intestine mirror checks mucous membrane of the whole large intestine and has not unusually found, pathology accords with the standard enteric and apt to defy the standard namely 1988 Rome's international conference of Rome of syndrome to put forward, could diagnose this disease.
The intestines are apt to defy syndrome to receive the extensive attention of medical circle in recent years, the position in they have illness coming on of the spiritual factor is paid attention to by clinician day by day. The important meaning re-recognized still lies in it can reflect the impact on this disease of the spiritual psychological factor better. A lot of scholars think: This one multifactor to influence and that determine the intersection of disease and group, cause of disease its and have illness coming on, involve and reflect " biology - psychology - sociology " Modern medical view that the medical mode realizes to disease.
Have further done the discussion to the morbidity mechanism of this disease in recent years, has changed and regarded IBS as a view of the simple enteric power disorder many years, realize this disease has viscera feeling unusual, colon increases to amazing sensitiveness, thus produce and suffer from abdominal pain, suffer from diarrhoea etc. and defecate unusually. And the unusual motive force disorder caused of this kind of feeling is adjusted and controlled by the nerve centre. The state of the nerve centre can influence IBS patient's symptom too. Think at present, emotion centre and controlling the plant centre that digestive tract sport, digestive juice secrete, endocrine regulation center, in the same dissection position. The interaction between the two, acting as the cause and effect of each other, IBS symptom is that physiology and psychological society of large intestine should surge the result of interacting.
Use some factors that patients are afraid to be regarded as " Malignant seeing and hearing is stimulated " Repeat to patients, can obviously improve the sensitivity that a patient expands to the rectum gasbag, it does not have the above-mentioned function on normal people that these irritate, indicate the conditioned reflex can influence the abnormal state of patient's viscera feeling of this disease. In addition offer low dose of 5 alternative - the intersection of hydroxy and the intersection of color and amine absorb and then inhibitor, act on the nerve center, can lighten symptom of IBS patient, this indicates too the centre has regulation and control to the intestines function. The brain scans to find the atlas of the blood flow of IBS patient's brain is different from healthy people after the rectum is expanded. Learn and check and observe IBS patient and difference with the brain picture between the health people in magnetic resonance image of the functionality. The research is for IBS patient's nerve centre to unusually follow the disorderly direct evidence that puts forward of the enteric function for the first time. Enteric dish and connection sum between nerve centre interact and is called that " The brain intestines are interdynamic " .
About the risk factor of this disease, there is a new view too: Should defy sum ' Or) It is all important morbidity inducements that the intestine are infected. The bacterial gastroenteritis patient follows for half a year and observes, 25% of the patients the intestines function happen disorderlily. Find in the epidemiology investigation to IBS of Beijing area, the dysentery history is positive to result in the danger of this disease to take place to rise by 2 times. It still shows to study, the morbidity of the enteric function disorder increases with extension of the course of disease of dysentery enteritis, when the course of disease of dysentery enteritis is 1- 2 weeks, increase by 2.5 times than person shorter than one week danger degree of the enteric function disorder. There is dysentery IBS patient of the enteritis history, the inflammation medium is expressed and increased in its terminal ileum, second form colon and rectum intersection intestines mucous membrane. Must cross person that acute intestine infect why only 20%- 25% people suffer from IBS, but do not most people have disease? Determine whether IBS has illness coming on, and its psychological quality exchanges the sense factor, in crossing the person that the acute intestine infect, only those possess some spiritual psychological quality, such as the depression quality or person irritated by a certain great life, it is apt to suffer from IBS.
The scholars infer the information that the immunity change can be transmitted to the centre after the intestine are infected, influence the state of the nerve centre; And some factors influencing nerve centre, for instance depressed, anxious, great spirit is stimulated, can also influence the immunoreaction of the intestine by linking the mechanism between the nerve and immunity, thus participate in the morbidity mechanism of IBS after infecting.
Pain, especially chronic pain and depression often exist at the same time. Pain is that a kind of complicated physiological psychology reacts, always follow emotional responess. Pain can aggravate, even cause the emergence of depression. Some chronic pain patients often have obvious cognitive function twisting and helpless senses. Pain exerts an important influence on their life, make the corresponding social remuneration reduce, social activities are reduced, self-control and self-actualization drop. Some patients even regard pain and living environment as the crushing one.
In the enteric apt symptom of surging syndrome, it is one of its numerous symptoms to suffer from abdominal pain, can affirm, the psychological factor plays an important role while development happens in it.
Foreign relevant scholars, when it is apt to surge the syndromic relation with spiritual symptom to count the intestines, find some patients have psychological obstacle at various degrees, among them anxiety, depression, hysteria are seen more. The mood obstacle begin, come from the intersection of patient and understanding in disease and worry, and the load disturb with anxious to aggravate symptom of intestine, form vicious circle. Thus, the intestines are apt to defy syndrome to be a kind of physical and psychological disease.
At present, it is enteric and apt to surge the diagnosis of syndrome and treat often at internal medicine department, and internist get used to, offer intestines and stomach the intersection of power and medicine, spasmolytic, have an ease constipation medicine, adjust enteric the intersection of function and medicine and sterilization preparation medicine always, and ignored the application against depressed medicine, the therapeutic effect is often unsatisfactory, cause the course of disease to delay, has aggravated the patient's mood obstacle conversely, even lost confidence to the treatment. So, if can break " mood - symptom " Chain of this vicious circle, very important for the transferring to returning and recovering of disease, this and resist the application in intestines and stomach function disorder disease of anxious medicine to offer the theoretical foundation for antidepressants. So, when physicians are diagnosing and treating the function disorder patient of intestines and stomach, should collect more patient's life and relevant information of the mood, and appraise the patient's symptom and mood synthetically. To the heavier one of those depressed, anxious mood, can offer antidepressants or sedative. Selecting to use in antidepressants, can select the Fluorine west spit of fland, one hundred excellent solving, west man, happy and special of handkerchieves of hydrochloric acid for use. Insomnia person and the serious one of anxious symptom, can select stable and librium,etc. for use. Certainly, it is essential to complement with certain psychotherapy and adjust medicine of the stomach.
The intestines breaking out repeatedly are apt to surge syndrome, can treat with antidepressants, the most frequently used with Third Ring Road antidepressants. Find handkerchief Rossi spit of fland may be more effective in recent years.
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