Intestinal cancer assists radiotherapy Radiotherapy _'s treatment before the skill

Intestinal cancer assists radiotherapy Radiotherapy _'s treatment before the skill
Another usage that intestinal cancer assists radiotherapy is the radiotherapy before a skill.
Employ radiotherapy to have the following advantages before the skill: The blood of target cells is supported well, inferior ammonia content is high, the sensitiveness to the ray is high, curative effect is good. It can make tumour dwindle to radiate, pathological change lowers one (down-staging) ,Thus improve the excising rate of tumour, not only the cutting rate of the root is improved, protect the success rate of anus also obviously improve. The small intestine is obviously shrunk by the range shining, the incidence that the radioactive small intestine damages is obviously reduced too. Take place resume intestine continuously, radioactive proctitis, identical mouth narrow, and enteric the intersection of function and the intersection of obstacle,etc. and probability of complication greatly reduce too. The membrane fiber of sacral bone muscle increases thick after radiation, the protective action of blood vessel is strengthened to the sacral bone, damage intravenous chance less in front of the sacral bone, especially to some the intersection of progress and issues of pathological change in the skill, operation security is relatively improved, there are so many advantages in radiotherapy before the skill, but there is a fatal shortcoming, the ones that may not need radiotherapy to a part carry on radiotherapy, this is to treat excessively, because radiotherapy damages normal cells certainly after all.
In addition, especially emphasize it to the correct assessment of patient disease one before the skill at present, a series of inspection of examining through Ultrasonography B, pelvis CT/MRI, simulation intestines mirror in clinical examination, etc., comparatively assess the disease period of pathological change correctly, offer the basis for radiotherapy before the skill, avoid the unnecessary and not appropriate treatment.
Have 12 about can excise rectal cancer, carry on random research report of radiotherapy in front of the skill at least from middle period of the seventies to the present, but not employed the whole dosage (been greater than or equal to 45Gy) ,The radiation technology that the majority adopts is not very satisfied, do not have enough intermittence period (4~6 weeks) to finish the time that the late arrival performs the operation from radiating ,Only the recuring rate of 6 pieces of report part had statistics meanings finally.
A group of reports of Sweden 1183 accept radiotherapy before simple operation or operation + short-term skill separately, radiate the dosage 25Gy, finish employing 3 or 4 to shine in 5 days wildly, carry on the operation in one week after radiotherapy, the result reveals the recuring rate of part obviously drops (27% vs1% Plt; 0.001),Survival rate is obviously raised ((48% vs58% P in 5 =0.004). But two groups of proportions of accepting A-P excision are the same ((59% vs58%) ,So the scheme of radiotherapy has not got the American counterpart to agree to 5 days of the last week such as skill in Sweden, the latter thinks this scheme has several shortcomings: Not suitable for carrying on chemotherapy at the same time; Helpless to improving the success rate of protecting anus operation; The postoperative complication incidence increases. Paty,etc. thinks the greatest advantage of radiotherapy is to help to improve the success rate which protected anus operation before the skill.
Minsky report 30 low-order rectal cancer draft from the anus predestination 1.5-6cm A-P excise skill, after radiotherapy before 5040cGy the whole dosage skill, 83% have finished excising the anal canal anastomosis of colon before the low order.
Rouanet 78% after reporting the radiotherapy before the skill of low-order rectal cancer too do it to protect the anus operation. The radiotherapy before such skill, the operation needed to postpone going on 8-10 weeks at least, increased the distant place of tumour and sowed the scattered danger, many scholar carry on, put new aid that chemotherapy combine together treat in front of the skill recently for this reason, the result will be very prominent in the near future, will cooperate with postoperative chemotherapy again, to preventing sowing scatteredly, it is totally possible to improve in 5 and survive on the reasonable theory, certainly, the conclusion will wait for the result of following up a case by regular visits to for a long time to verify finally.
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