The new method _'s symptoms of differentiation of tuberculosis of intestine and Crohn's disease

The new method _'s symptoms of differentiation of tuberculosis of intestine and Crohn's disease
Courtyard Dr. Tian of sweet China of gi medicine of China's Western medicine of university of Sichuan, under the guidance of tutor Professor OuYang Qin, great professor of step, have verified the chain reaction technology of polymerase measures the intestines and lives and examines the tubercle bacillus DNA while organizing, it is a very valuable new method of tuberculosis of intestine of differentiation and Crohn's disease. On issuing the American intestines and stomach disease published in May of this year and studying the magazine in this research results, and is regarded as this institute " Foundation and clinical research of Crohn's disease " A part of the subject, obtain the first prize of progress prize in science and technology of Sichuan Province.
Crohn's disease is a kind of intestine chronic granulation swollen disease with unidentified reason, it lay finding and the intersection of pathology and the intersection of person who change and respect, have a lot of similarity with tuberculosis of intestine in clinical manifestation, the intersection of colon and mirror. So, the differential diagnosis of the two is very difficult, face a great difficult problem in bed.
Both the misdiagnosing rate is up to 65%, still lack the ideal differentiation method at present each other for the literature report. Many scholars proposed a lot of differentiation indexes from respects such as clinical manifestation, inner mirror finding and pathologic characteristic,etc. in the past, but demonstrate greater limitation while using clinically.
Obviously, the best differentiation method is to find the tubercle bacillus while organizing from the intestines, but a traditional one resist acid bacillus dye and tubercle bacillus train far from, satisfy, need while being clinical because of question in respects such as its sensitiveness, specificity and measuring the speed,etc..
Sichuan the intersection of university and the intersection of institute and gi medicine, Western medicine of China, apply the intersection of Crohn and disease and differential diagnosis of tuberculosis of intestine to the intersection of polymerase and the intersection of chain and the intersection of reaction and technology, the result is encouraging.
They, to the finding of 39 cases of tuberculosis of intestine and 30 Crohn's diseases, the sensitiveness of this method is 64.1%, the specificity is 100%, accuracy is 9.9%, the positive and negative predicted value is 100% and 68.2% respectively, indicate this method is an extremely valuable new method of tuberculosis of intestine of differentiation and Crohn's disease. The ones that may present in order to prevent PCR technology are false and positive and false and negative, they have adopted strict" operate aseptically " , improve specificity to guide thing, it sets up masculine gender to be and negative to contrast, repeat experiment a lot of measures.
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