Nutrition treat the best scheme _'s treatment of Crohn's disease in the intestines

Nutrition treat the best scheme _'s treatment of Crohn's disease in the intestines
Nutrition is Crohn's disease (Crohn'SDisease, CD) The important links being treated. Prevent the particles such as protein, fat or food additive of possible antigenic composition in food from bringing out disease activity on one hand, on the other hand take in and reduce, absorb the bad, pathologic losing and impact on absorption and use of the nutrient component of therapeutic medicine. Lead to the fact CD patient often presents the nutrition obstacle.
It is one of CD outstanding clinical manifestation to be malnutritive, the shortage of important nutrient component and energy, make the organism in catabolism state, incidence and mortality of various complications increase, according to condition and patient's psychological or physiological basic characteristic. Employ nutrition support, can relieve intestinal inflammation, improve nutritional status, resistance and recovery to promote organism of patient effectively with higher speed in right timely and appropriately. So nutrition supports to be one of CD treatment important means, have equal importance with medicine, surgery,etc..
Nutritive preparation have with overall nutrient component characteristics, can offer essential for human body energy, nutriment, vitamin, microelement in an all-round way in being enteric. Guarantee patient's normal physiological supersession and living needs. Zhu Feng, Wang Li builds, the Qian 's chirps,etc. the scholar's research reveals, the nutrition group has 22 examples (70.97%) before treatment in the intestines Need the nutrition outside the intestines, it is the nutrition in the complete intestines to treat and begin to carry out the transition in 2 weeks.
Analysis of variance through dividing into groups at random. Before treating, group's one's own nutritional status of nutrition is even bad under the situation of the control group equally in the intestines, nutrition group's weight and albuminous level obviously rise in the intestines after treating, hemoglobin level is apparent to rise; And weight of control group and albuminous level obviously drop before relatively treating. Explain on the nutritive the intersection of preparation and foundation nutrition support way as nutrition in the intestines, compared with simple ordinary meal, it is fully effective.
Nutrition (TPN) outside thinking and moving about one should select the whole intestines and stomach for use at Crohn's disease in the past As the main nutrition way, in order to guarantee the fully " having a rest " of enteric section of pathological change ,But intestine special nutriment glutamine of alimentary deficiency outside the whole intestines and stomach, the intestine lose machinery stimulating and direct nutrition of food at the same time, cause the mucous membrane of intestines to wither. Intestine immune protective screen the intersection of lymphocyte and phenotype change in the middle and upper cortex, leather organization restrain in the relevant and lymphocytic and netted intestine, a group of little ecology of intestinal fungus is out-of-balance. The intestines protective screen function is damaged. Inflammation aggravating patient's intestine of Crohn's disease instead reacts.
Studies have suggested, nutrition can be through improving the content of pathogenic antigen of macromolecule such as one group of environments of intestinal fungus and reducing protein and fat in the intestines of nutritive preparations such as meals and non- key element meals of key element,etc.. Achieve the goal of reducing the intestine with exposed mucomembranous antigen, and the direct nutrition of nutrient liquid contributes to enteric and mucomembranous repair; Thus improve the enteric and mucomembranous integrality and prevent the losing of protein. Clinical research show, nutrition superior to nutrition outside the intestines obviously in the intersection of intestines and the intersection of mucous membrane and penetrating and the intersection of blood plasma and the intersection of glutamine and the intersection of level and in the nutritive intestines of preparation.
Key element if meals one hundred contain glutamine also in being general and plain, have the intersection of nutrition and small intestine and improve the intersection of intestine and immune function of function. Nutritive preparation can offer abundant vitamin and microelement. Can avoid the inflammation progress reacting. Promote the intestines mucous membrane after damaging to grow and repair. Nutritive preparation does not also need or less likely to need digesting, do benefit to absorbing, residue few characteristics, make the intersection of pathological change and enteric piece carried far to lie in get not abundant " Have a rest " ,Help the intersection of activity and a pathological change relieve.
Zhu Feng, Wang Li builds, in the research that the Qian 's chirps etc., the group CDAI before treatment of nutrition is obviously higher than the control group in the intestines. A patient takes the activity 87.10% ( 27/ 31) ,Prove the intersection of activity and period competent nutritive preparation in CD nutrition feasible in being enteric. Crohn the intersection of disease and condition relieve closely related to improvement of patient's nutritional status. In the intestines at the 2 week such as treatment such as group such as nutrition, clinical symptom begin, take a favorable turn, every activity index (include of CD: Globulin, 2 globulin, CRP and ESR) Drop to some extent, clinical several symptom already relieve at the 4 week. Every activity index is dropped to normally, explain the improvement that nutrition contributes to a condition of CD activity in the nutritive preparation intestines, will not aggravate the condition at least.
In the activity period of CD. What hormone is induced and relieved basically treats the measure. The intersection of nutrition and group and control group each have l5 examples in the intestines ' 48.39% ) With 3 ' 37.5% ) A patient uses hormone in activity. But hormone treatment, reduce calcium to absorb and increase the bad reaction of protein catabolism,etc., unfavorable to the improvement of patient's nutritional status; And apt to produce hormone dependence leads to the fact that it is difficult to dismiss from medicine. Nutrition can substitute the hormone treatment safely, effectively, reach and keep relieving in the intestines, avoid the purpose to recur.
So until nutrition, as nutrition treatment of main fact, the intersection of Crohn and disease, especially hormone reliance type the intersection of Crohn and the intersection of disease and treatment of patient choose in being enteric. In the choice of enteric inner nutritive preparation, it is relatively high to CDAI (namely activity is relatively strong) CD patient,can at first use key element meals. Such as one hundred general and plain or Ellen being many. After the condition is steady to some extent, change into whole protein preparation. If can all one's effort or good and plain. In numerous key element meals preparations. One hundred is general and plain relatively better, mainly because it absorbs the respect in protein except that 15% amino acid absorb the route, and 85% short peptide absorbs the route, these short peptide compositions not only will not be regarded as the antigen and caused the quick intestine, physiology protein approaching normal people even more instead absorbs the mode.
In addition, how low, difficultly to cause the side effect of diarrhoea than Ellen one hundred general and plain infiltration is pressed. Usually compare with Ann that can't be used in the diabetic without sucking and the meal fiber, can not only contain the meal fiber with all strength. Can also be used in the diabetic, treat the first-selection of whole protein preparation of CD. One of CD pathogenesis is thought to relate to the fact that it is excessive that fatty acid of the short chain is produced. And the function of the meal fiber is just lain between and leads for fatty acid of the short chain, so supplementing the meal fiber can utilize too many short chain fatty acid to give play to and improve the cellular capacity of colon to lack and promote and damage the function that the mucous membrane repairs, help pathological change to resume.
In a word, the nutrition in the intestines of nutritive preparation, CD patient's fully effective nutrition supports the way. The activity in CD is feasible in period. Contribute to the improvement of the condition. Can be regarded as the substitution of hormone and treated the choice, the treatment of disease has great meanings.
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