How the liver fiber disappears _ is therapeutic

How the liver fiber disappears _ is therapeutic
Not only the intersection of animal and the intersection of model and research indicate liver fiber take reversible, have relevant research indicate people the intersection of liver and fiber take likewise reversible, the research develops and evokes researchers to oppose the liver fiber and treat the enthusiasm studied. How does the liver fiber disappear? The understanding of this question mainly comes from animal's experiment at present.
Britain Iredale,etc. shows the skin becomes one kind of cells and macrophages play an important coordination role in the liver fiber is absorbed in the fiber, in addition, ground substance metal protease organizes inhibitor - a (TIMP-1) Act on too very crucial. TIMP-1 become fiber express in the one kind of cells in the intersection of star and cell and skin of activating mainly.
TIMP-1 can already inhibit the protease activity of ground substance (inhibit the ground substance from degrading) ,Can resist and wither and die albumens through inducing - -Bcl-2 expresses, and then promote the fiber to produce cell hyperplasia. The fibrous absorption organizing relates to the fact that TIMP-1 expresses dropping, when TIMP-1 expresses to drop, the substrate including that N - calcium sticks albumen and Model I collagen etc. of possible enzymolysis of metal protease.
The organization transfers to glutaninase and lies between collagenous thread led to hand in and unite and work too in the ground substance is reabsorpted, because this kind of collagen can make the liver cicatrix tissue degrade, resist ground substance protease to unite to make, especially to the going on reduced tissue of cell.
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