's general knowledge of new early warning index of liver cirrhosis progress

's general knowledge of new early warning index of liver cirrhosis progress
A new research reveals, hyaluronnidabe of serum is a early warning index of liver cirrhosis patient's condition progress.
GPT and ASP transaminase is used in the detection index of patient's liver function of virus hepatitis for a long time. Recently, the extent of damage of liver that the researcher proposes measuring the serum hyaluronnidabe level of the empty stomach and finding out about the liver cirrhosis patient.
The researcher of Edinburgh University points out, the hepatocyte needs a plurality of steps to production and supersession of hyaluronnidabe, hyaluronnidabe to fill the intersection of quality and the intersection of cell and synthetic the intersection of candy and amine, gather candy among the one, it degrade course, need, lie between, lead through peculiar receptor by the intersection of liver and the intersection of sinus and the intersection of crack and endothelial cell.
In order to find out about the generation process of hyaluronnidabe and change in liver cirrhosis patient's body, the researcher has analyzed disease patient's empty stomach serum hyaluronnidabe level of 221 cases of chronic liver.
The result of study reveals, liver cirrhosis patient's serum hyaluronnidabe level is higher than other chronic liver diseases notably. The average 440 of serum hyaluronnidabe of 127 cases of liver cirrhosis patient, 95% CI: 367-515; The serum hyaluronnidabe mean value of 60 cases of chronic hepatitis is 63, 95% CI: 37-91; 11 cases of fatty liver patient, the hyaluronnidabe mean value of serum is 107, 95% CI: 37-177.
Though the hyaluronnidabe level causes liver cirrhosis in many kinds of causes of disease, including alcohol hepatitis and one's own immunity hepatitis patient are similar; But the liver damages the more seriously, the higher the serum hyaluronnidabe level is.
Hyaluronnidabe horizontal gt of serum; At 100 o'clock, diagnose the specificity of liver cirrhosis is 78%, sensitiveness is 83%; Act as hyaluronnidabe horizontal gt of serum; At 300 o'clock, the specificity rises to 96%.
Hyaluronnidabe level and the liver cirrhosis patient's density of plasma albumin, blood platelet are counted and the bilirubin level is correlated with, and not found that correlate with serum GPT level.
The researcher draws the conclusion, the hyaluronnidabe level of the empty stomach measures diagnosis liver cirrhosis that can be effective, especially those are not suitable for becoming a bioptic patient.
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