Categorised _'s general knowledge of cause of disease of liver cirrhosis

Categorised _'s general knowledge of cause of disease of liver cirrhosis
1. Virus hepatitis and liver cirrhosis took cause of disease of liver cirrhosis of our country 40% - 65% , Mainly caused by B, third, man type hepatitis virus, among them the most common one is hepatitis B. It has illness coming on immunity that the mechanism causes with the hepatitis virus unusually has something to do. Its pathogenic way is mainly to pass chronic hepatitis, especially chronic active hepatitis stage, and develop into liver cirrhosis gradually. Most of liver cirrhosis after hepatitis are shown as great nodular liver cirrhosis: A few cases such as courses of disease delay slowly, inflammation necrosis and pathological change are lighter but relatively even, can also be shown as little nodular liver cirrhosis. Develop from virus hepatitis to the course of disease of liver cirrhosis, it is very short to several months, it is long to decades.2. Alcohol liver cirrhosis accounts for about 7% of liver cirrhosis of our country, but in the past few years, with the improvement of people's living standard, the consumption to the wine of our country is rising year by year, especially the area to the north of the Changjiang River. So, should cause and watch out for alcohol liver cirrhosis. 3. Send ox worm liver cirrhosis infect blood fluke or liver fluke,etc., cause more. The blood fluke depends on for a living the mesenterium intravenous branch. The worm's ovum mainly deposits gathering together the area under control, the stimuli of worm's ovum and toxic product behind entering liver with the blood flow, cause a large number of hyperplasia of connective tissue, cause liver fiber and door pulse and high pressure. The blood fluke left leaf of liver cirrhosis is given much trouble more seriously, liver surface have bigger tubercle, get rid of neighbouring worm's ovum, deposit hepatocyte of place, have, wither other some hepatocyte obviously change the sex and regenerate, so liver function change relatively slight at being clinical, and door pulse appear relatively early under high pressure, called it snail fever liver cirrhosis in the past, should be called the snail fever liver fiber. 4. The poisonous substance is long and bright with medicine liver cirrhosis to contact some chemical poisonous substance repeatedly, for instance arsenic, phosphorus, tetrachloromethane; And take some medicines for a long time. If first Quito bar, tetracycline, two the people sulphur oxygen and different smoke of night of dawn of chlorine take off first ammonia butterfly chanting, a pair of vinegar phenol to mix etc.. Equal. 4 causes the hepatocyte necrosis. The bile is deposited. Or anaphylactic inflammation reacts in the liver. Thus cause chronic hepatitis and develop into liver cirrhosis finally. 5. Supersession liver cirrhosis Caused some materials to deposit in the liver because of supersession obstacle by heredity and supersession disease. Cause sex change necrosis, cell of A, form the interconnected system to organize hyperplasia and form liver cirrhosis. An important one is as follows, a.the iron supersession is disorderly: See at the hemochrome disease. b.Copper supersession is disorderly: See and change the sex in the liver lenticular nucleus namely the intersection of Wilson and disease. C.a1 - resist tryptic deficiency disease (a1- Antitrypsin deficiency) . d.Glycogenic to accumulate the four type (Typely ghycogensis) disease . e.Galactose blood disease (Talacto-saemia) . f.Hydroxyphenylaminopropionic acid supersession disorder disease (Tyrosinosis) When. 6. Liver intravenous reflux blockage liver cirrhosis Obstructive disease of the vein causes liver cirrhosis such as cypress to check syndrome (Buddchiari syndrone) , contracting narrowly. The intersection of L and Yan Bao, chronic and in heart failure, cause long-term extravasated blood of the liver, so that hepatocyte oxygen deficiency necrosis. The fibrous hyperplasia of connective tissue, and cause liver cirrhosis. 7. The bile is deposited or the bile duct is blocked while existing continuously outside the liver in the bile liver of liver cirrhosis, can cause hepatocyte to be ischemic organizing hyperplasia and forming liver cirrhosis by necrosis, fiber. Because bile duct obstruct person who cause as primary in the liver; Obstructed by the bile duct outside the liver Cause the sound in order to continue taking place 8. It will cause liver cirrhosis whether malnutritive liver cirrhosis is malnutritive, for a long time, been lacking the evidence all the time. Most scholars think. Malnutritive can lead to the fact protein containing Dan amino acid reduces, the production of hepatocyte inner enzyme reduces, trend towards the lipoprotein material. Protein that choline or synthetic choline needs is scarce, phosphatide that the inner and neutral fat of liver is synthetic reduces, cause the intersection of hepatocyte and fat pile up, change the sex, take place fatty liver, form liver cirrhosis finally. But a scholar thinks malnutritive and direct fatty liver It is big. But long-term alimentary deficiency. Cause the hepatocyte to reduce to other resistance of causing the cause of disease to be plain, enable some intestines endotoxin after people's liver of portal vein, the liver is unable to remove it effectively, thus cause hepatocyte sex change necrosis, and form liver cirrhosis. 9. The congenital syphilis liver cirrhosis pregnant woman passes to due to foetus by the placenta after being infected with syphilis. 10. Latent source hard to turn by the intersection of patient and medical history and organize pathology check, can't make a definite diagnosis of liver cirrhosis of cause of disease their liver.
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