Every index meaning _'s symptom of liver function

Every index meaning _'s symptom of liver function
What does every index of the function represent?
The project of checking in commonly used liver function is as follows,
1,Valley - third transaminase (ALT, GPT) Consult value 0.0-40U/L;
2,Valley - transaminase of grass (AST, GOT) Consult value 0.0-41U/L;
3, - valley ammonia acyl is transferred to peptide enzyme (GGT) Consult value 5-50U/L;
4,Alkaline phosphatase (ALP, AKP) Consult value 15-121U/L;
5,Total bile acid (TBA) Consult value 0-12umol/L;
6,Total albumen (TP) Consult the value 60-85g/L albumin (Alb, A) Consult value 40-55g/L globulin (Glb, G) Consult value 20-30g/L;
7,Total bilirubin (TBil) Consult value 0-20umol/L direct bilirubin (DBil) Consult value 0.0-5.6umol/L indirect bilirubin (IBil) Consult value 1.7-17.3umol/L.
Although so many data have given you a start, its upper and lower fluctuations each have meanings, the main clinical meaning is as follows,
1-4 enzyme inspections that is main. Hepatocyte, when the necrosis, various enzyme in the hepatocyte release blood on, lead to the fact enzyme index increase.
1,ALT: Damage one of the most sensitive indexes for the hepatocyte, is mainly distributed in the hepatocyte. It is seen at fatty liver that light - intermediate to increase, chronic hepatitis, liver cirrhosis, hepatocarcinoma, snail fever, the intersection of heart and disease, the intersection of gallbladder and disease, use behind the some medicines, chemical drug poisoning,etc., increase, see on acute virus hepatitis, acute poisoning hepatitis,etc. notably.
2,AST: Mainly distributed and organized in cells, the most in myocardium cells, secondly it is in the hepatocyte. Increase, see on acute myocardium infarction, traumatism, hepatocarcinoma, behind the fierce sport, use behind,etc. the some medicine. The ones that should especially pointed out should notice the ratio of ALT/AST is changed, gt; It is light that 1 is briefed on acute hepatitis and chronic hepatitis; lt; 1 is briefed on liver cirrhosis, hepatocarcinoma, serious disease and hepatitis, liver necrosis, myocardium infarction; If lt; 3 is usually primary hepatocarcinoma.
3,GGT: Distribute over hepatocyte mao detailed bile duct and bile duct system extensively. Increase, meet at anxious chronic pancreatitis, the intersection of gallbladder and disease slightly, it is seen at urgent chronic virus hepatitis, alcohol hepatitis, hepatocarcinoma, increased to see at pancreas cancer,etc. notably that intermediate to increase. The patient of the obstructive jaundice obviously rises.
4,ALP: The majority comes from liver, skeleton, small intestine, kidney,etc.. Increase, see on getting obstructive jaundice, jaundice hepatitis, liver cirrhosis, rickets, use behind the some medicines, increased gt notably; 500U/L person, should watch out for malignant pathological change.
5,TBA: Decompose to emerge in the liver from cholesterol. Increase, see, on urgent chronic hepatitis, liver cirrhosis, hepatocarcinoma,etc., it has on chronic hepatitis, especially diagnosis of liver cirrhosis to be relatively high value.
6,TP, Alb, A, Glb, G, A/G: A/G ratio is 1.5-2.5: 1,When liver function is damaged, can appear total albumen reduce, A/G ratio reduce even invert, the general albumin reduces the intensity and is parallel to severity of hepatitis. Chronic and heavy-duty hepatitis and liver cirrhosis patient's albuminous density are reduced, globulin increases at the same time, A/G ratio inverted.
7,TBil, Dbil, IBil: Used for judging jaundice type and jaundice intensity.
Through the above understanding, we have known importance and complexity of checking in liver function. If checking will unusually combine the comprehensive analysis of the medical history, can't adopt a casual attitude!
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