Friday, March 1, 2013

The liver function of hepatocarcinoma is checked with operation _'s symptom

The liver function of hepatocarcinoma is checked with operation _'s symptom
The liver is human body's biggest substantive organ, are bearing the complicated and various physiological function, including formating, supersession, transshipping and excreting,etc.. When various cause the hepatocyte damage or internal and external biliary tracts of liver to obstruct originally, can cause various substance metabolism (such as protein, fat, candy, bilirubin and bile acid,etc.) in the hepatocyte Abnormal state,on the other hand because of liver it is penetrating in cell membrane damage sex increase or membrane structure, make inner enzyme of afterbirth overflow. Cause supersession product and acid content related to liver in the blood to change.
Check liver function to the hepatocarcinoma patient: Contribute to the severity that understands liver damages, is chosen the rational healing solution; Assist diagnosis and differential diagnosis of hepatocarcinoma; Used for predicting whether to recur after the operation is excised, and the prognosis is judged. Commonly used liver function check, include bilirubin metabolize and protein metabolism, the intersection of enzyme and supersession and dyestuffs excrete the intersection of person who test and respect mainly at the clinic, it is concrete it serum project bilirubin, it is white /globulin, albumen swimming, third amino acid transaminase (ALT) electric , one glutaminic acid is transferred to peptide enzyme ( - GT) The intersection of thrombinogen and time,etc..
1.It express more hepatopathy activities high that bilirubin serum bilirubin is entered, the obstructing yellow value or later period of course of disease. Total bilirubin gt; 30 mol/L person should not carry on the surgery; gt; 20 mol/L person, it should be prudent to make big hepatocarcinoma and excise.
2.White the intersection of globulin and the intersection of absolute value and albuminous absolute value reflect effective total number of hepatocyte obviously expose when the intersection of liver and chronic and serious injury. The normal value of albumin is 35-55g/L, lt; 30g/L is unsuitable to excise the great operation. Peoples normal is white for 1.5-2.5 ratio in ball,it is white /invert, be reflected ball ratio whether liver function be compensated to be lost, it is difficult to tolerate the great operation.
3.Third amino acid transaminase (ALT) ALT is unusual, often reflect liver essence cells are damaged, or reflect a large amount of necrosis of tumour. The patient ALT of tumour obviously increases, the mortality of operation obviously increases too.
4. one glutaminic acid is transferred to peptide enzyme ( - GT) Hepatocarcinoma is enormous, the portal vein has extensive cancer bolts inside, when liver function is unusual, - GT obviously rises, there is influence greatly on operation or prognosis.
5.Time of thrombinogen (PT) PT obvious extension, shows liver function is damaged seriously, the prognosis is relatively bad. It is unsuitable to carry on the operation at 50% o'clock that it is worth normally that PT is lower than.
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