What danger does the portal vein that liver cirrhosis causes have under high pressure? 's general knowledge

What danger does the portal vein that liver cirrhosis causes have under high pressure? 's general knowledge
The high pressure of portal vein is that the pressure of portal vein increases. The portal vein refers to a bigger vein of the of liver population, intravenous from the mesenterium and the spleen vein was converged, divided into No. 2 Branch and entered people's liver on the liver door. 75% of blood of the liver come from the portal vein, 25% come from the liver artery. Mainly responsible for collecting the intravenous blood of the gullet, stomach, intestines, pancreas, gallbladder and spleen.Under the normal situation, the pressure of portal vein is 700-1,500 handkerchieves, exceeds 2.0 kPas and has a clinical meaning promptly. Puncture by leather spleen pressure can represent the pressure of portal vein often in the spleen that measure.In the liver at the time of liver cirrhosis or the blood flow blockage of portal vein outside the liver, can make the venous pressure of the door increase, in addition, congenital development is bad, deformity or tumour oppression,etc. makes the door pulse pressure increase. These pathological changes can cause the substantive damage of little leaf of liver, such as hepatocyte sex change necrosis, capillary network are destroyed, continue and organize hyperplasia with tubercle, connective tissue, fiber in liver. As time passes deform blood vessel in the liver, obstruct, cut off, the blood flow is deposited. As the liver vein flows out one while obstructing seriously, the ischemic oxygen deficiency of hepatocyte, aggravate necrosis of the hepatocyte. Make the resistance in the liver increase. In this case, the door vena cava can only be in order to increase one's own shrink pressure, increase and increase the thick blood vessel to compensate definitely. Form the high pressure of portal vein as time passes. The long-term portal vein causes a series of complication under high pressure, such as presenting congestive splenomegaly, intestines and stomach, peritoneum chronic to congest and collateral circulation set up, claim portal vein hyperbarism. The high pressure of portal vein will lead to the fact the oesophageal fundus of stomach is variceal, belly wall and rectum are variceal. As the esophagus and fundus of stomach are variceal becomes certain, under external factor function, can break, cause upper digestive tract massive haemorrhage. Shown as a kind of stool of spittinging blood in a large amount or pitch; Cause the rectum vein to break and have blood in one's stool in a large amount while bleeding. Portal vein high pressure will present the intersection of spleen and swelling, abdominal distension, receive difference, abdominal cavity many internal organs function hyperfunction in extravasated blood, spleen. The spleen is swelling and it make erythrocyte, leucocyte and blood platelet destroy, increase that the spleen function is hyperfunction, cause anaemia and whole blood alike to reduce, immunological function low, organism resistance drops. The high pressure of portal vein is a direct factor of forming ascites, peritonitis, septicaemia too. The appearance of the ascites, it is often apt to cause the blood volume of effective circulation to be insufficient, the blood pressure and dropping, electrolyte are disorderly, involve the function of many kinds of internal organs such as the heart, brain, kidney,etc.. These serious amalgamation diseases, jeopardize the patient's life at any time.
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