Which are the cause of disease of liver cirrhosis? 's general knowledge

Which are the cause of disease of liver cirrhosis? 's general knowledge
Liver cirrhosis is a kind of common chronic disease. A lot of people mention liver cirrhosis right away become terrified at the news. In fact, liver cirrhosis can be prevented, so long as more pay attention to in daily lifing can play a role in preventing liver cirrhosis. There are a lot of causes of disease of liver cirrhosis, the following factors can cause liver cirrhosis.
1.Virus hepatitis: In our country the virus hepatitis is (especially B-mode and C-mode) It is a main reason for causing liver cirrhosis, among them the majority develops into pulse liver cirrhosis of the door. The liver cirrhosis patient's hepatocyte often shows HBsAg positively, its positive rate is up to 76.7%.
2.Chronic alcoholism: Can account for 60%- 70% of the total number at liver cirrhosis caused by alcohol hepatopathy of American-European countries.
3.Alimentary deficiency: Animal's experiment shows, feeds the animal which lacks the choline or methionine food, can develop into liver cirrhosis through fatty liver.
4.The poisonous substance is poisoned: Some chemical poisonous substance such as arsenic, tetrachloromethane, yellow phosphorus,etc. can cause liver cirrhosis while acting on the liver for a long time.
The mechanism is a going on fiber that liver cirrhosis mainly has illness coming on. The normal liver is organized collagen (I and type) of a quality Mainly distributed around area under control on the door and central vein. I type obviously increases and calm in the small leaf with the collagen at the time of liver cirrhosis. With the intersection of sinus and the intersection of crack and inner constant deposition of collagen, endothelial cell window Kong Ming apparent to reduce, make the liver sinus develop into the capillary gradually, cause the material exchange obstacle among blood and hepatocyte. A large number of collagen of liver cirrhosis comes from lying in the crack (Disse) of sinus Store lipoprotein cell (Ito cell) ,This cell increases life to jump, can transform into one kind of cells of fibrous master cell. Outgrowth fiber organize, form light pieces of Suo, connect, form interval and reconstruct the intersection of liver and little leaf at the structure each other yet initial stage, called the liver fiber. If continue progress, the central district of little leaf will connect with the fibrous interval of places such as the area under control of the door,etc. each other, make the little leaf structure of liver and blood circulate and reconstruct and form liver cirrhosis.
|