What is the emergence mechanism that liver cirrhosis erupts the spontaneous peritonitis simultaneously? 's symptom

What is the emergence mechanism that liver cirrhosis erupts the spontaneous peritonitis simultaneously? 's symptom
Liver cirrhosis patient's other internal medicine departments are apt to erupt peritonitis simultaneously, its pathogenesis may relate to following several points. (1)The germ enters the chance of the abdominal cavity to increase: Sending infecting the focus mainly in intestine, biliary tract, urinary tract originally of this disease, the pathogen is blue with the leather negative bacillus is much. Martini,etc. discover liver cirrhosis the intersection of small intestine and top, jejunum, ileum of patient have Escherichia coli all bacterium breeds, and normal people are except that the ileum has a few bacteria, there is no bacterium's growth in the other positions of small intestine. The cirrhosis patient causes viscera vein congesting and lymphatic vessel expansion because of door pulse and high pressure in later period, not only produce the ascites but also can cause intestines mucous membrane congesting, edema or rotten, make the mucomembranous protective screen of intestines defend the function to reduce. Especially when the intestine are infected, the bacterium is apt to invade the abdominal cavity from the intestine through the lymphocytic system or intestines wall. The door pulse pressure increases at the time of liver cirrhosis, intestine, inner bacterium and lymphocytic liquid with fungus of portal vein can be overflowed from liver sinus wall of extravasated blood, seeped in the abdominal cavity by the lymphocytic clump of liver door, or fit with liver vein to prop up or short out and enter systemic circulation directly through the door - systemic circulation by the portal vein, so that cause bacteremia and abdominal cavity to infect. (2)The organism defends the function to weaken: On one hand until liver single and nuclear and the intersection of macrophage and systematic function destroy the intersection of liver cirrhosis and patient, the liver is removed in the blood the ability of the bacterium is reduced, on the other hand often have malnutritive, low albumen blood diseases because of the liver cirrhosis patient, cause complement insufficient, immunoglobulin (Ig) density reduce and leucocyte hasten, take function, subside etc., have created conditions for the bacterium invaded. Intestinal bacteria breed in a large amount at the time of liver cirrhosis, the bacterium antibody rises, make the organism produce unusual immunoreaction, the organism resists infection ability further drops. Unless at the time of ascites in liver cirrhosis, because dilute a large amount of liquid,at ascites immunoglobulin (Ig), complement reduce and hasten to take function to subside leucocyte, make the leucocyte wound the function and weaken to the directness of the pathogen. And contain abundant albumen, candy and electrolyte in the ascites, it is culture medium of an ideal bacterium, make the bacterium apt to grow to breed in the ascites. Various factors such as diarrhoea can make organism immunity reduce ing, the upper digestive tract bleeds, uses hormone for a long time, employs immune inhibitor, surgery, inappropriate application antibiotic and increases various operation of the enteric inner pressure, if inner mirror check and rectum mean examine, enema,etc., intravenous inner intubate, abdominal cavity puncture and gasbag clog with catheterization,etc. handling, may bring out a disease.
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