The metastasis of cancer of liver can predict _'s general knowledge
Can the metastasis of cancer of liver be predicted? The answer of research institute of hepatocarcinoma of Fudan University, subsidiary scientific research personnel of hospital of Zhongshan of Fudan University is definite.
Until famous soup, researcher of hepatocarcinoma, encourage the intersection of You and academician, head the list of signers, admire the intersection of human relations and show, Professor of leaf Qinghai responsible " metastasis of cancer of liver recurs and predicts the research group " Finish with the intersection of U.S.A. and state-run the intersection of heart and big the intersection of researcher and cooperation Wang, research institute of hygiene, " Employ the gene expression table to predict the metastasis of cancer of hepatocyte " The important achievement is issued on the magazine of Britain " natural medical science " published on March 17. Relevant experts think, this innovative research results are that clinic that metastasis of cancer of liver recured was predicted and prevented and cured and offered the important theoretical foundation, indicate hepatocarcinoma of our country is studied, reached a new level at the same time.
Hepatocarcinoma is the great disease endangering the people life and health of our country seriously, about 400,000 people die of hepatocarcinoma every year in the whole world, among them our country has accounted for over half. In 5 years after the hepatocarcinoma operation is excised, survival rate reaches about 40%, shift and recur after but there are operations of about half of patients. How to predict in early days, find that may shift the patient who recured in early days, and for prompt prevention and treat, further lengthen the key point that the hepatocarcinoma patient survives.
For this reason, admire the show of human relations, researchers such as leaf Qinghai and Wang XinWei,etc. set up high people hepatocarcinoma naked mouse's model and cell department who shifts latent energy in the research institute of hepatocarcinoma of Fudan University, a series of ones that find the shortage of the chromosome Sp is involved in metastasis of cancer of liver are studied on the foundation, employ the advanced genetic chip technology to select 153 genes correlated to metastasis of cancer of liver from more than 10,000 genes, take the lead in preparing the molecule model that can predict whether patient shifted cancer correctly in the world, and further verify the bone bridge albumen can be as judging the index of the prognosis of hepatocarcinoma and treating the target to click.
It is introduced, the hepatocarcinoma patient shifts the molecule model, it is the tumour organization fetching the patient first to use predicting, carry on the genetic analysis with relevant cancer and combine calculation, then contrast the result of calculation with model, can judge the possibility of the metastasis of cancer of liver, its rate of accuracy is more than 90%.
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