Tuesday, March 12, 2013

Liver cirrhosis immunology changes clinical meaning _'s symptom

Liver cirrhosis immunology changes clinical meaning _'s symptom
What is the clinical meaning in which liver cirrhosis immunology changes?
Liver withered to deny cell (Kupffer cell) when the liver cirrhosis Can't produce and engulf and strain function effectively, make the antigen in the blood of portal vein unable to be removed, so that high antigenic blood disease appears. Have already proved the antigen has mainly been the original fungus of intestines. A large number of antigen stimulates immunity such as spleen, lymph node to organize, cause specific immunoreaction, then has produced a large amount of immunoglobulin (Ig). Immunoglobulin (Ig) increase it is the intersection of intestines and original fungus that stimulate immunity organize and by B cells (plasma cell) outside the liver mainly Ig that produce increase, liver itself there is no ability to make Ig.
So, Ig, globulin and total globulin increases and the liver function test causing therefrom is unusual, they do not reflect directly the liver is damaged, can't be regarded as the index that liver function comments on. But these change reflects that quality among the liver cells are given much trouble with common pathologic foundation of formating, reducing, storing in of the leucocyte, so when globulin increases and reduces with the albumin, there is greater value on judging.
Globulin of liver cirrhosis increases with the organic change intensity of liver parallelly, rise, indicate organic to change obvious notably, prognosis bad then.
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