Monday, March 18, 2013

Liver cirrhosis causes _ general knowledge of endocrine regulation

Liver cirrhosis causes _ general knowledge of endocrine regulation

At the time of liver cirrhosis, some hormone in the blood will change, thus cause the manifestation of a series of endocrine regulation. The most common one has estrogen increasing, androgen that is reduced, and aldosterone, vasopressin increase, will also reduce glucocorticoid of renal gland sometimes.

When liver function fails, the liver can't eliminate surplus estrogen, aldosterone and vasopressin in time, lose, cause it to accumulate too much in body. After estrogen increases, inhibit the hypophyseal secretion function through the negative feedback mechanism, cause androgen to reduce, secrete and reduce the adrenocortical hormone too. The change of the hormone often causes the following endocrine regulation to behave.

1,It is swelling that the male patient presents the breast, the normal male breast will not increase, and some liver cirrhosis patients increase the breast, someone calls the man milk woman, but will generally go through it for one year to the course in several years.

2,The women patient has disorderly period, even amenorrhea, infertile, etc.

3,Sex and failing, the reproduction function drops, male patient and women patient can happen. Some male patients can find the sexual desire fail, the testis withers, sperm's quantity and quality drop, women can display and has not ovulated cycle incidence increasing or infertility.

4,The hair changes, the male patient can present the hair to loss, beard and body mao are reduced.

5,Pigmentation can take place in places such as face department, shank and the upper abdomen,etc., particularly in order to often rub the place obviously. It is obvious in the palm line, milk fainting area to observe finding.

6,In addition, it is can at patient face, shank, at chest, shoulder carrying, and upper limbs,etc. position, expand spider's mole, capillary; Palm appear erythema, these to because estrogen increase
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