Wednesday, March 13, 2013

How does liver cirrhosis bleed to cause? 's general knowledge

How does liver cirrhosis bleed to cause? 's general knowledge
Nasal hemorrhage of nose, gums bleed, and skin purpura, ecchymosis, oesophageal fundus of stomach variceal to break, it bleeds to be liver cirrhosis and liver function fail and the intersection of blood coagulation and obstacle amalgamate disease while being common. The liver cirrhosis patient bleeds, often reflect that the condition is critical. Need treating and curing actively. The reason bleeding is:
The blood coagulation factor is turned into and reduced.
The quantity of blood platelet is reduced and the function is unusual: The blood platelet occupies the important position in the whole styptic course, the decline of its quality and quantity is unfavorable to arresting blood. Often hyperfunction with splenomegaly and spleen function at the time of serious liver cirrhosis, make a large amount of blood platelet delayed in the spleen, destroy and accelerate. In addition the bone marrow function is inhibited, can also make the quantity of the blood platelet reduce at the time of liver cirrhosis, the function is unusual.
The anticoagulatory material increases: Heparin is the important anticoagulation material, but can be decomposed by Heparin enzyme, make it lose anticoagulatory function. Synthetic Heparin enzyme of liver reduces, makes Heparin in the blood circulation increase at the time of liver cirrhosis, the blood is difficult to solidify.
Fibrinolysis increases: The last stage of the course of blood coagulation forms the fibrin, the fibrin can be dissolved by fibrous protease. The liver can't remove the activator of fibrous protease effectively at the time of liver cirrhosis, therefore has increased dissolution of the fibrin.
The blood vessel is damaged: Skin damage in the blood vessel when the liver cirrhosis, capillary penetrating the intersection of and increase but incident to bleed. Still because the pressure of portal vein increases at the time of liver cirrhosis, the esophagus and fundus of stomach are variceal, it is easy to be damaged and broken and bled.
Blood coagulation in the filling the air blood vessel: Systematic function obstacle of the single nuclear macrophage, can't remove and urge to congeal the material effectively at the time of liver cirrhosis, in addition the cover is damaged in the blood vessel, activate the blood coagulation system, blood coagulation in the extensive blood vessel happens, need to consume a large number of blood platelet and blood coagulation factor, can cause the function obstacle of blood coagulation.
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