Treatment and liver transplantation _'s treatment of hepatocarcinoma

Treatment and liver transplantation _'s treatment of hepatocarcinoma
Hepatocarcinoma jeopardizes malignant tumour of health and life seriously. Say strictly, there is not a therapeutic method that have absolute assurance that cures all kinds of hepatocarcinoma at present. The method to treat hepatocarcinoma is numerous, it is unrealistic to let the patient choose out to be most suitable for one's own method from it, let some the intersection of liver and the intersection of disease and specialized doctor make decision this, can offset to some extent too. So, find out about indication of different therapeutic method, it is very essential to making the correct judgement.
Before 1990s, the liver excises the best therapeutic method consistently voted hepatocarcinoma, also hepatocarcinoma is got
Hope of effecting a radical cure. In fact, liver excise and regional chemotherapy make right curative effect really. Small 5 the intersection of annual mean and survival rate of hepatocarcinoma close to 70%, survival rate is close to 40% too big 5 in hepatocarcinoma. However, the patient who can make liver and excise only accounts for about 30% of all hepatocarcinoma patients, in addition most patients do not have operation chance, main reason have liver too bad to store function and tumour unable to excise to infringe main blood vessel already and position excise getting difficult specially.
In recent years, some new therapeutic method, if microwave solidification, radio frequency melt, high and can be focused on supersound, radioactive focus knife, alcohol injecting, radioactive particle and planted the appearance that treats etc. into, frozen, have brought the new hope for those hepatocarcinoma patients who can't become the excision. The wound of these method is relatively little, easy to operate, the risk is relatively low, can yet be regarded as a kind of choice. But is not eliminated completely because of pathological change, so the recuring rate is relatively high, its long-term curative effect still remains to further observe.
The intersection of liver and the intersection of artery and the intersection of chemotherapy and thromboembolism, involvement commonly called ased to that is treat, perform the operation the intersection of curative effect and better one under treatment, later period hepatocarcinoma suitable for, occur frequently hepatocarcinoma, hepatocarcinoma break, bleed and preparation, hepatocarcinoma prepare etc. in front of the skill of liver transplantation in front of the enormous skill of hepatocarcinoma. As to in there can make is later period hepatocarcinoma life cycle lengthen 1 about year to 50% about patient. Can make about 30% of the patients excised as to big hepatocarcinoma. As to the liver transplantation patient of hepatocarcinoma, such as getting involved and treating before transplantation, can reduce the recurring of tumour after liver transplantation.
The rise of the transplantation technology of liver, has brought the revolutionary change to surgical idea of the liver, liver transplantation not only can excise tumour, the more important thing is to remove the liver of whole disease at the same time, \ eliminating hepatocarcinoma and happening " The soil \ " ,The new liver transplanted has removed the liver and stored the worry not complete of the function. Liver transplantation treat the intersection of liver and hard compound and little hepatocarcinoma made the satisfactory result, and got unanimous approval of the domestic and foreign expert, survival rate has already been up to 80% its 5 years after the operation. Though liver transplantation treats hepatocarcinoma with bringing the bright prospect to us in practice in theory, but its indication should be mastered strictly, not every hepatocarcinoma patient adapts to doing liver transplantation. The international standard is: The single tumour diameter does not exceed 5 centimetres, or the tumour number does not exceed 3 centimetres without exceeding 3, each diameter. But in practice, for instance standard and American UCSF standard of Kyoto of Japan,etc. all relax some, have made better result too. Combining my national conditions condition, we think, has not shifted outside liver, there is not cancer bolt that take shape, the infringement without trunk is a bottom line of liver transplantation of hepatocarcinoma. And the skill pre-processing, the operation is operated, preventing, rational application of the immune inhibitor in the skill, measures such as postoperative chemotherapy,etc. have a important impact on prognosis of liver transplantation of hepatocarcinoma too.
The treatment of hepatocarcinoma is influenced by many kinds of factors. Size, property, number, and vascular neighbouring relationship and liver function state of tumour,etc., will all influence choice and result of patient's healing solution. So the patient reaches the hepatopathy treatment experiencedly, especially a medical organization understood in depth treats that is the wise selecting.
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